Synthesis and Reactions of Highly Protected 2-Mannosamines
碩士 === 國立臺灣大學 === 化學研究所 === 87 === Applying the chelation effect of magnesium atoms, it is available to select one or two deprotected hydroxyl groups from those on D-glucose. Moreover, deprotecting the C2 hydroxyl group of D-glucose, fully protected 2-manosamins are synthesized. So far, t...
| Main Authors: | , |
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| Other Authors: | |
| Format: | Others |
| Language: | zh-TW |
| Published: |
1999
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| Online Access: | http://ndltd.ncl.edu.tw/handle/89212783337567420637 |
| Summary: | 碩士 === 國立臺灣大學 === 化學研究所 === 87 === Applying the chelation effect of magnesium atoms, it is available to select one or two deprotected hydroxyl groups from those on D-glucose. Moreover, deprotecting the C2 hydroxyl group of D-glucose, fully protected 2-manosamins are synthesized. So far, the strategy we applied has more advantages than that on other reports in several aspects.
The fully protected 2-mannosamine has very good combinations of protection groups. That is, we can identify every functional group on 2-mannosamin. For these variable combinations, it contains excellent potential on the synthesis of sialic acid and its analogs.
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