The Exploration of Related Factors in Retinopathy of Prematurity

• Main Authors: Meei-Hwa Chyr, 池美華
• Other Authors: Chia-Yuh Chen MD, PHD
• Format: Others
• Language: zh-TW
• Published: 1999
• Online Access: http://ndltd.ncl.edu.tw/handle/47918958455200503351

碩士 === 中山醫學院 === 醫學研究所 === 87 === The aim of this study was to investigate risk factors for developing retinopathy of prematurity(ROP) in preterm babies and to describe regression of ROP. We also evaluated the differences in demographic data， medical intervention，laboratory data，and diagnosis between these preterm babies who suffered ROP or not. This study was performed retrospectively from Oct.1,1996,through September 30,1998.195 preterm(gestational age below 37 weeks and birth body weight below 2500 gm) were enrolled， who must stay in neonatal intensive care unit (NICU)for at least 28 days. Infants with congenital heart disease、congenital anomaly and loss follow up for 3 months were excluded. Data were analyzed by chi-square test，t-test and logistic regression. In this study，retinopathy of prematurity was found in 112 infants (53.4%).Among these ROP infants regression rate was 85%.This study also showed that birth body weight，gestational age，use of mechanical ventilator and surfactant，Hemoglobin，Anemia、diagnosis、body weight at 28- day-old，blood transfusion，period of NICU admission and O2 duration were significant difference in developing ROP in preterm infants. Logistic regression analysis indicated that O2 duration and body weight at 28-day-old were correlation with developing ROP.In summary，careful monitor and nursing care may also an important role for preventing development of ROP in preterm infants.