Design and Synthesis of Pyrrolo[2,1-c][1,4]benzodiazepine Hybrid Agents

Design and Synthesis of Pyrrolo[2,1-c][1,4]benzodiazepine Hybrid Agents

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碩士 === 高雄醫學院 === 藥學研究所 === 86 === The pyrrolo[2,1-c][1,4]benzodiazepines (PBDs), a family of potent DNA-binding antitumor antibiotics , are produce by streptomyces species. These drugs react covalently with DNA to form an N2-guanine addu...

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Bibliographic Details
Main Authors:	Hsu, Mei Hui, 許美惠
Other Authors:	Jeh-Jeng Wang
Format:	Others
Language:	zh-TW
Published:	1998
Online Access:	http://ndltd.ncl.edu.tw/handle/50956882661194243769

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