| Summary: | 碩士 === 高雄醫學院 === 醫學研究所 === 86 === A case-control study was designed to investigate the relation
between cancer mortality and residents in communitites within
1km radius of a petrochemical industry at Chienchen District in
Kaohsiung City.We obtained cases data from the death certificate
during 1986-1997.July and selected matched controls with
condition that sex,age(+2∼-2years) and case:control=1:2.The
data was collected from the next-of-kin of cases and matched
controls by using the face-to-face interview questionaire.The
association between possible factors and cancer risk among all
cancer cases,lung cancer case and non-lung cancer cases and
matched controls was evaluate.Conditional logistic regression
analysis was used to access the possible effects of risk
factors.Our result showed that the risk factors such as smoking
cigarette, drinking wine,chewing betel nut and residing duration
was significant high.Cigarette smoking still played a main role
of causing cancer comparing with nosmokers,the odds ratio
individually was 4.17 (95%CI=1.60-10.85),2.64(95%CI=0.58-12.02)
and 3.66(95%CI=1.53-8.77) among three study population.In
addititon,the residing duration had an increasing risk
trendency.And we found the inverse association for high frequent
consumption of
fruit(0.33,0.16-0.69;0.25,0.08-0.79;0.35,0.16-0.77).These
finding shows that the more fruit they take,the better
protective effect they will obtain.Additionally,we found smoking
cigarette and residing duration have a synergistic effect.
Therefore,we estimate the attributable risk proporation,included
three potential factors smoking cigrette,residing duration and
taking in fruit.Specially,the attributable risk about residing
duration are 55.5%,37.2%and57.8% for all cancer cases,lung
cancer cases and non-lung cancer cases and matched controls.
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