| Summary: | 博士 === 中國醫藥學院 === 中國醫學研究所 === 86 === The purpose of this study was to observe the biochemical and pathological effects of ru-yih-jin-huang-saan (RYJHS) and jie-guu-saan (JGS) on experimental fracture healing of the rat. Seventy-five rats were fractured in the middle of left tibia and fibula by the standard manual method. They were divided randomly into experimental and control groups. They were intraperitoneally injected with Ringer''s solution, used RYJHS externally or fed with JGS respectively. The animals were executed at 4, 8, and 12 days after fracture. The contents of hydroxyproline, synthesis of DNA, RNA, and protein, trace element analysis, radiation and pathological studies were observed.
The results demonstrated that the experimental groups were earlier and more thorough than the control group, especially in the combined group of RTJHS and JGS, in the collagen formation, bone cell metabolism, enzyme system, x-ray and pathological studies
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