Didital Analysis of Ultrasonograms of Canine Diffuse Liver Disease

• Main Authors: Yu, Yi Ming, 于宜民
• Other Authors: Chaw Chian Ho
• Format: Others
• Language: zh-TW
• Published: 1997
• Online Access: http://ndltd.ncl.edu.tw/handle/40228535093706337368

碩士 === 國立中興大學 === 獸醫學系 === 85 === SummaryThis research is to study for the changes in hepatic ultrasonographic echo brightness of hepatic diffusive damages caused by artificial acute poisoning;and whether there is a correlation between changes of echo brightness and thedegree of histopathological damages. In order that we may establish an ultrasonographic digitization technique of liver disorder for clinical veterinarian use.Nineteen dogs were divided in two groups, sixteen in treatment group and three in control group. Treatment group animals were given three large doses of acetaminophen within 24 hours. Hepatic ultrasonographic scanning and blood biochemical examination were performed twelve hours before and after the treatment . High resolution 7.5MHz linear probe were used to scan on 4 sections: right 10th inter costal transverse plane; right and left subcostal oblique plane; caudal of xyphoideus transverse plane.The ultrsongraphic images were recorded and print-out on the Mitsubishi video copy processor machine as well as connected to a 586 personal computer and stored in the read&writable magneto optical laser disc. So that we could perform image analysis by Osiris public program from Netscape in order to compare with the clinical symptoms, the serological results and the hepatic pathological changes.In the treatment group, 10 cases died within 72 hours (natural death cases) and cases endured over the period of time (enduring cases). There is no difference in echo brightness of control group and enduring cases(p>0.05), yet a decrease in natural death cases were observed (p<0.05). A procical curve appeared in natural death cases when plotting the echo brightness against time of treatment; yet the curve in enduring cases is declined first and then risen later.The results of histopathological examination showed that the hepatic tissue were most damaged in the cases died in between 61 to 72 hours, the less damaged in the cases died between 24 to 60 hours, and the least damaged in cases died within 24 hours of treatment. This phenomenon implies the recovering of damages. We may try to explain the relationship with the echo brightness and histopathological result and give advance in the further research.