| Summary: | 碩士 === 中國醫藥學院 === 環境醫學研究所 === 85 === Abstract
For analyzing the correlation between blood lead level (BLL) and
blood pressure (BP) in youngster, the subjects of this study was
focused on the children under 15years of age. The blood
specimens and related information of the children under 15 years
were collected from the nation-wide survey - Nutrition and
Health Surveillance in Taiwan - hosted by the Institute of
Biomedical Science, Academia Sinica, and sponsored by the
Department of Health. Several prior researches suggested low
dose of BLL would he possible negative impacts on the
development of neural system and intelligence among youngsters.
Those impacts sometimes would also trigger high blood pressure.
Yet, findings as such never proved to be conclusive. This study,
therefore, using cross-sectional design and multivariate
regression analysis techniques aims to understand the scope of
effect to BP by BLL.
A total of 1,322 children aged between four and fifteen years
old were recruited to be the subjects of this study during
1994/1996. The mean age of the subjects was 10.0 years old
(SD=3.2 years old); mean of BLL was 5.5 μg/dl, (SD= 2.2 μg/
dl, ranging from 1.1 to 19.1); mean of systolic BP was 103.9 mm
Hg (SD =12.4 mm Hg), and mean of diastolic BP was 64.6 mm Hg
(SD= 11.7 mm Hg). The results calculated by Pearson's
correlation matrix indicated that statistically significant
correlations were found botbetween BLL and systolic BP.
Nevertheless, further multivariate analysis showed that the
determinants of BP included age and body mass index.But BLL
exhibited no effect to BP.
Our preliminary results reveal no solid correlation between BLL
and BP. Possible explanations to the outcome include relatively
small number of high BP occurrences among the children surveyed,
confounding effect between BLL and other risk factors. However,
due to the fact that increasing number of researches on
environment as well as occupational disease suspect the
correlation between BLL and BP, to explore the correlation
occurring among children remains a vital public health issue
worth further study
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