A study of the electrophysiological effect of N-allyl-N- methyl-2- (3,4-methylenedioxyphenyl)-ethylamine (HF-Ⅴ-15) on cardiac tissues.
碩士 === 國立臺灣大學 === 藥理學研究所 === 84 === HF-Ⅴ-15 是合成小分子生物鹼,在大白鼠心臟組織具有稍微增加收縮力 及減慢心跳頻率的作用。本篇論文主要研究 HF-Ⅴ-15 在大白鼠及天竺鼠 心臟組織的電生理學,並研究其抗心律不整的作用機轉。 1、在大白鼠心 房及心室組織,HF-Ⅴ-15 (3∼30μM) 會使收縮力隨濃度增加而略為增強 ,並使右心房自發性跳動頻率減慢。 2、在離體天竺鼠心臟組織中,HF-...
Main Authors: | Lin,Wang-Jong, 林王忠 |
---|---|
Other Authors: | Su,Ming-Jai |
Format: | Others |
Language: | zh-TW |
Published: |
1996
|
Online Access: | http://ndltd.ncl.edu.tw/handle/90768512568572360468 |
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