| Summary: | 碩士 === 國立臺灣師範大學 === 化學系 === 84 === AbstractAlthough it has a wide range of application in industry,
cadmium is considered to be a highly toxic element in the
environment. It is known that cadmium will interact with some
Metallothionein（MT）in humam body and be excreted through
urine. This process may play the role of detoxification of Cd
poisoning.Due to the complexity of urine matrix and low
concentration of Cd in human urine, size-exclusion
chromatography, microwave digestion, Chelex-100 preconcentration
and Zeeman graphite AA techniques are applied to the
determination and speciation of Cd and Cd-MT in human urine
samples.The results show the concentration of Cd in human urine
is lower than 1.00 ng/mL and the method detection limit observed
is 0.058 ng/mL. About 80% of urinary cadmium is in liquid-urine
and about 50% of liquid-urinary cadmium is Cd-MT. The accuracy
of determinations is confirmed by the analysis of Standard
Reference Materials.
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