| Summary: | 碩士 === 中原大學 === 醫學工程學系 === 84 === Early diagnosis and treatment of cardiovascular diseases are
important.Traditional, invasive cardiocathetered methods were
used to study the detail hemodynamics and myocardial property
.However, it is uncomfortable to the patient. In this study, a
method that evaluate the left ventricular performance using
cardiac magnetic resonance images were derived. The derived
method that uses non-invasive cardiac MR imaging to reveal the
relation of myocardial mechanic property and cardiac pump
function. This relation is derived from the change of LV
chamber area and myocardial area.It is the ratio of Young's
modules （stress/strain, T/L）and elastance(E). The derived
relation is called TLE relation. The Young's modules is the
ratio of stress and strain of myocardium. The stress of
myocardium is directly proportional to pressure. The Elastance
is the ratio of the change of pressure and the change of
volume. Therefore, pressure can be canceled. Then, the TLE
relation can be describe as function of the change of LV
chamber and myocardial area . The relationship between TLE and
LV chamber area is a second- order polynomial function. This
relation can be the index of cardiac performance. Five sets of
multi-phases, multi-slices (MPMS)short-axis cardiac magnetic
resonance images were used to evaluate left ventricular
contractive function. Four patients were with hypertension-
hypertrophied cardiovascular disease.One is a 21 year-old young
male without cardiovascular disease.For each image slice of
each subject, the relation between TLE ratio and LV chamber
area follows the common trend line.However,it is time consuming
in acquiring MPMS MR images. The TLE relation of single-phase,
multi-slices（SPMS） MR images were tested against MPMS MR
images. The result agrees to our prediction.The TLE relation of
MPMS and SPMS has a positive correlation.This result suggests
taht SPMS MR imaging can be used to evaluate LV contraction
function.
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