| Summary: | 博士 === 中國醫藥學院 === 中國醫學研究所 === 84 === The allergic rhinitis was grouped into yin xu gan re （yin vacuity liver heat）, fei jing yu re（lung channel depressed heat）, biao wei bu gu（insecurity of exterioe defense）, fei qi xu（lung qi vacuity）, pi qi xu（spleen qi vacuity）, shen yan xu（kidney yang vacuity）and shen yin xu（kidney yin vacuity） based on the theory of the traditional Chinese medicine. Yin xu gan re and fei jing yu re were termed as the heat pattern and the others as the vacuity pattern, respectively. The allergic symptoms were easily triggered by stimuli such as dust in heat pattern patients and their allergic screen test was positive. In addition, IgE level and eosinophil counts of heat pattern patients were higher than those of the vacuity patients. Abnormal secretion of cortisol, malfunction of adrenal cortex and low metabolic rate were found in vacuity cold patients after further investigation. The characteristics of vacuity cold were that patients had allergic symptoms when they were tired or exposured to wind and cold and got worse during the physical status changing from yin to yang in the morning. The lower cAMP/ cGMP ratio play an important role for the trigger of allergic symptoms in vacuity cold patients also.
The allergic rhinitis symptoms were improved after treated with pu shen chu han prescription for vacuity cold patients and tzu yin ching je prescription for heat pattern patients. The treatments for the mixed pattern patients are tzu yin ching je and pu shen chu han, which tzu yin ching je was administered first, and then pu shen chu han. By the treatment of wen yang pu shen, the abnormal secretion of cortisol, malfunction of adrenal cortex, even epinephrine and norepinephrine, which were secreted from adrenal medulla, all were improved. While the cAMP/cGMP ratio was increased also.
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