The Effect of Hydrophilic/Hydrophobic Ratio on Polyurethanes Blood Compatibility

• Main Authors: Da Shion Jon, 江大勳
• Other Authors: Liu Chin Hsin
• Format: Others
• Language: zh-TW
• Published: 1995
• Online Access: http://ndltd.ncl.edu.tw/handle/86897090278941968389

碩士 === 國立臺灣科技大學 === 化學工程研究所 === 83 === Polyurethanes were synthesized from mixtures of PEG hydrophilic ） and PTMG （hydrophobic ） as soft segments， and MDI-1，4 BD as hard segment. ESCA， DCA， and AFM were used to study the effect of hydrophilic/hydrophobic soft segment ratio on the surface structure of polyurethanes. Its effect on mechanical properties and blood compatibility were also investigated. Microphase separation on polyurethane surfaces was studied by ESCA. From ESCA data， we found that， with the depth of 30A， the surface fraction of ether group increased with the molecule weight of PTMG and decreased within %PEG. However， the surface fraction of ether group increased with %PEG for deeper surface （about 100A）. From DCA data, we found that PU surface was most hydrophobic with 30﹪ PTMG， and the hysteresis was largest. It implied fast molecular mobility， and substantial phase separation. We also found that the advancing angle increased with the molecule weight of PTMG， means the surface becomes increasingly by hydrophbic. The blood compatibility was best when hydrophilic/hydrophobic ratio was at 1:3. Under such condition， PU surface was also smoothest as shown by AFM. The PU surface was roughest and the blood compatibility was worst when the hydrophilic/hydrophobic ratio was at 9:1. ESCA analysis showed the best compatibility was correlated to a surface with 28﹪~35﹪ surface fraction of ether group.