SAR of Unfused Polyaromatics as Potential Antitumor Agents

碩士 === 國立中山大學 === 化學學系 === 82 === The aims of the thesis are the synthesis of bicyclic, tricyclic and tetracyclic unfused polyaromatic compounds as potential antitumor agents or amplifiers of bleomycin and theirAR( structure activity relati...

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Bibliographic Details
Main Authors: Huang, Tase-Mian, 黃彩綿
Other Authors: Ong, Chi-Wi
Format: Others
Language:zh-TW
Published: 1994
Online Access:http://ndltd.ncl.edu.tw/handle/61528809994956123840
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Summary:碩士 === 國立中山大學 === 化學學系 === 82 === The aims of the thesis are the synthesis of bicyclic, tricyclic and tetracyclic unfused polyaromatic compounds as potential antitumor agents or amplifiers of bleomycin and theirAR( structure activity relation). The dimers of the unfused polyaromatics having at least three aromatic ring are capable of inhibiting cencer cell growth. The length of the side chainnd the heteroatom used can influence its antitumor activity.