A Study on Sex Hormones in Gingival Crevicular Fluid and Black Pigmented Bacteria in Subgingival Plaque of Pregnant Women

碩士 === 高雄醫學大學 === 牙醫學研究所 === 82 === Gingivitis is one of the most common oral diseases, which is caused by dental plaque and by the factors produced/released from it. The black pigmented bacteria in subgingival dental plaque is thought to be the pathogens of the gingivitis. Prevotella inter...

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Bibliographic Details
Main Author: 陳冠先
Other Authors: 蔡吉政
Format: Others
Language:zh-TW
Published: 1994
Online Access:http://ndltd.ncl.edu.tw/handle/53678181023601981524
Description
Summary:碩士 === 高雄醫學大學 === 牙醫學研究所 === 82 === Gingivitis is one of the most common oral diseases, which is caused by dental plaque and by the factors produced/released from it. The black pigmented bacteria in subgingival dental plaque is thought to be the pathogens of the gingivitis. Prevotella intermedia and Porphylomonas gingivalis have been shown to be closely associated with human gingivitis. These two kinds of black pigmented bacteria can use female sex hormones such as progesterone or estradiol as a source of nutrients. In pregnant women, the concentrations of progesterone and estradiol are markely increased in serum and both of them are accumulated and found in the gingival tissue. The purpose of this study was to test levels of female sex hormones in gingival crevicular fluid and to observe the relationship between hormones and black pigmented bacteria in subgingival plaque. The results showed that the level of progesterone found in the gingival crevicular fluid of pregnant women was markedly higher than that of women in postpartum stage. The percentage of black pigmented bacteria in subgingival plaque were also higher than that in postpartum stage, and both results were statistically significant. Percentage of black pigmented bacteria was positively correlated with both the progesterone level, pregnancy and the severity of the gingivitis. Severity of the gingivitis was positively correlated with both the plaque index and the percentage of black pigmented bacteria in subgingival plaque.