Studies on the Active Constituents of Coriaria intermedia Matsum.

• Main Authors: Lin Ming Shiung, 林明薰
• Other Authors: Chang Yuan shiung
• Format: Others
• Language: zh-TW
• Published: 1994
• Online Access: http://ndltd.ncl.edu.tw/handle/79865864037351537276

碩士 === 中國醫藥學院 === 中國藥學系 === 82 === Coriaria intermedia Matsum is a famous folk medicine in Taiwan for the treatment of bellyache、carbuncle and rheunatism. Recent studies had found that the extracts from Coriaria genus were exhibited significant anti-tumor and antipsychotic activity. The methanolic extract of roots and the boiling water extract of leaves were partitioned and then separated by chromatography. Five different solid components were isolated. Based on physical ,chemical,spectral of the corresponding compound.Those components were identified as phytosterol、 ellagic 3,3'-dimethyl ether、D:C friedoolean-8-en-3-ol-28-oic acid、coriamyrtin、β-tutin. One of them, D:C friedoolean-8- en-3-ol-28-oic acid was founded from the Coriaria genus for the first time. The results of pharmacological experiment showed that the n-hexane、chloroform、ethyl acetate、 n-butanol fractions from the root of Coriaria intermedia had obvious inhibition of the tumor cell,P-388.