Development of matrix materials for direct compression of ontrolled release dosage forms

碩士 === 台北醫學院 === 藥學研究所 === 81 === The results indicated that the physical properties of the tablets are good. Larger amount of Surelease ( The aqueous dispersion of 25% ethylcellulose ) used in the formulation ( 1% to 10% ) would result...

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Bibliographic Details
Main Authors:	Harn Ying Wang, 王涵瑩
Other Authors:	Ming Thau Sheu
Format:	Others
Language:	zh-TW
Published:	1993
Online Access:	http://ndltd.ncl.edu.tw/handle/84857448661289204786

id	ndltd-TW-081TMC00551006
record_format	oai_dc
spelling	ndltd-TW-081TMC005510062016-02-10T04:08:52Z http://ndltd.ncl.edu.tw/handle/84857448661289204786 Development of matrix materials for direct compression of ontrolled release dosage forms 直打用間質性控釋材質之開發研究 Harn Ying Wang 王涵瑩碩士台北醫學院藥學研究所 81 The results indicated that the physical properties of the tablets are good. Larger amount of Surelease ( The aqueous dispersion of 25% ethylcellulose ) used in the formulation ( 1% to 10% ) would result in slower drug dissolution. There shows no significant difference of characteristics between lactose and dicalcium phosphate. Compared to commerical pro- duct, the controlled release dosage forms developed in this study present a slower release rate and higher extent of AUC. Above all, it is proved to be developing matrix materials for direct compression of controlled release dosage forms using two common-used excipients of lactose and dicalcium phosphate. Ming Thau Sheu 許明照 1993 學位論文 ; thesis 87 zh-TW
collection	NDLTD
language	zh-TW
format	Others
sources	NDLTD
description	碩士 === 台北醫學院 === 藥學研究所 === 81 === The results indicated that the physical properties of the tablets are good. Larger amount of Surelease ( The aqueous dispersion of 25% ethylcellulose ) used in the formulation ( 1% to 10% ) would result in slower drug dissolution. There shows no significant difference of characteristics between lactose and dicalcium phosphate. Compared to commerical pro- duct, the controlled release dosage forms developed in this study present a slower release rate and higher extent of AUC. Above all, it is proved to be developing matrix materials for direct compression of controlled release dosage forms using two common-used excipients of lactose and dicalcium phosphate.
author2	Ming Thau Sheu
author_facet	Ming Thau Sheu Harn Ying Wang 王涵瑩
author	Harn Ying Wang 王涵瑩
spellingShingle	Harn Ying Wang 王涵瑩 Development of matrix materials for direct compression of ontrolled release dosage forms
author_sort	Harn Ying Wang
title	Development of matrix materials for direct compression of ontrolled release dosage forms
title_short	Development of matrix materials for direct compression of ontrolled release dosage forms
title_full	Development of matrix materials for direct compression of ontrolled release dosage forms
title_fullStr	Development of matrix materials for direct compression of ontrolled release dosage forms
title_full_unstemmed	Development of matrix materials for direct compression of ontrolled release dosage forms
title_sort	development of matrix materials for direct compression of ontrolled release dosage forms
publishDate	1993
url	http://ndltd.ncl.edu.tw/handle/84857448661289204786
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Development of matrix materials for direct compression of ontrolled release dosage forms

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