Synthesis of (^^ )-(5^^ ,7^^ ,8^^^^)-3, 4-Dichloro-N-methyl-N-[ 3-methylene-2-oxo-8-(1-pyrrolidinyl)-1-oxaspiro [ 4,5 ] dec-7-yl ] benzeneacetamides and related compounds as irreversible ligands for the kappa-opiate receptor
碩士 === 國立臺灣大學 === 中國藥學研究所 === 78 === (±)-(5ξ,7α,8β)-3,4-Dichloro-N-methyl-N-[3-methylene-2-oxo-8-(1-pyrrol- idinyl)-1-oxaspiro[4,5]dec-7-yl]benzeneacetamides(1a和1b) 已被合成出，可作 為具有選擇性和不可回復性的Kappa 受器的結合劑。這兩個化合物是以可回復性的K- appa- 結合劑...
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| Format: | Others |
| Language: | zh-TW |
| Published: |
1990
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| Online Access: | http://ndltd.ncl.edu.tw/handle/03670049648086036847 |