Insights into the Iimmune Mechanisms Leading to Lupus-like Autoimmunity in New Zealand Black Mice

Systemic lupus erythematosus (SLE) is a chronic, multi-organ autoimmune disease characterized by the production of antibodies against self nuclear antigens. Genetics play a dominant role in disease pathogenesis and functional examination of spontaneously-arising lupus-prone animal models has provide...

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Bibliographic Details
Main Author: Pau, Evelyn Yin-Wah
Other Authors: Wither, Joan
Language:en_ca
Published: 2013
Subjects:
Online Access:http://hdl.handle.net/1807/43707