The Identification of Novel Proteins that Interact with the GLP-1 Receptor and Restrain its Activity
G-protein coupled receptors (GPCRs) have been shown to interact with an array of accessory proteins that modulate their function. I hypothesize that the GLP-1R, a B-class GPCR, similarly has interacting proteins that regulate its signaling. An unliganded human GLP-1R was screened using a membrane-ba...
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| Language: | en_ca |
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2013
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| Online Access: | http://hdl.handle.net/1807/42870 |