Chronic Mitochondrial Translation Inhibition Alters Metabolic Phenotype and Stemness Properties of a Leukemic Cell Line
Recently, we demonstrated that the anti-bacterial agent tigecycline preferentially induces death in leukemia cells through the inhibition of mitochondrial protein synthesis. To better understand the mechanisms of sensitivity and resistance to mitochondrial translation inhibition, we treated TEX leu...
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| Language: | en_ca |
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2012
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| Online Access: | http://hdl.handle.net/1807/42395 |