B Cell Development: The Impact of the Environment

B lymphocytes develop from pluripotent stem cells, and differentiate to plasma cells (PCs) in reaction to signals from the supportive microenvironment. Different sets of signals, which are derived from multiple sources such as soluble cytokines and cell-cell contacts, are required at different stage...

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Bibliographic Details
Main Author: Simard, Nathalie
Other Authors: Paige, Christopher J.
Language:en_ca
Published: 2013
Subjects:
Online Access:http://hdl.handle.net/1807/35997

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