Characterization and Inhibition of the Dimer Interface in Bacterial Small Multidrug Resistance Proteins
As one of the mechanisms of antibiotic resistance, bacteria use several families of membrane-embedded α-helical transporters to remove cytotoxic molecules from the cell. The small multidrug resistance protein family (SMR) is one such group of drug transporters that because of their relative small si...
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| Language: | en_ca |
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2012
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| Online Access: | http://hdl.handle.net/1807/34849 |