Examining a Role for Planar Cell Polarity Signaling in Endothelial Cell Alignment and Organization

Endothelial cells (ECs) respond to flow but the exact mechanism producing alignment is not completely understood. We characterized EC alignment in microfluidic channels, 4 mm wide by 350 um high, to generate shear of 20 dynes / cm2 across the cell surface. In microchannels, ECs aligned perpendicular...

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Bibliographic Details
Main Author: Brunetti, Jonathan A.
Other Authors: McGuigan, Alison P.
Language:en_ca
Published: 2012
Subjects:
Online Access:http://hdl.handle.net/1807/33497