A Computational Study of Proton Uptake Pathways in Cytochrome c Oxidase

Cytochrome c oxidase (CcO), the terminal enzyme in the electron transport chain, couples proton pumping to the reduction of dioxygen into water. The coupling mechanism remains to be elucidated. Previous studies have identified several mutations within CcO's primary proton uptake pathway (the D-...

Full description

Bibliographic Details
Main Author: Caplan, David
Other Authors: Pomès, Régis
Language:en_ca
Published: 2012
Subjects:
Online Access:http://hdl.handle.net/1807/33352