Inhibition of Transthyretin Fibrillogenesis Using a Conformation Specific Antibody
Immunoglobulin-mediated inhibition of amyloid fibril formation in vivo is a promising strategy for the treatment of protein misfolding diseases such as the amyloidoses. Here we focus on transthyretin amyloidoses, a group of protein conformation diseases caused by the misfolding of the serum protein...
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| Language: | en_ca |
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2012
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| Online Access: | http://hdl.handle.net/1807/32230 |