The Role of CCL5/RANTES in Regulating Cellular Metabolism in Activated T cells

Recruitment of effector T cells to sites of infection is essential for an effective adaptive immune response. The inflammatory chemokine CCL5/RANTES activates its cognate receptor, CCR5, to initiate cellular functions including chemotaxis. This thesis describes the signaling events invoked by CCL5 a...

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Bibliographic Details
Main Author: Chan, Olivia
Other Authors: Fish, Eleanor N.
Language:en_ca
Published: 2011
Subjects:
Online Access:http://hdl.handle.net/1807/30539