Disruption of the Toll-like Receptor 4 Signaling Pathway by Salmonella Effector SigD
The enteropathogenic bacteria Salmonella are the main cause of food borne gastroenteritis worldwide. The activation of Toll-like receptor 4 (TLR4) by LPS triggers an immune response to counter infection. Signaling by TLR4 requires the adaptor proteins, TIRAP and TRAM. Recruitment and activation of t...
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| Language: | en_ca |
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2011
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| Online Access: | http://hdl.handle.net/1807/29614 |