A Phenomic Assessment of Yeast DNA Damage Foci using Synthetic Genetic Array Analysis and High-content Screening
Aberrant DNA synthesis and maintenance have been implicated in numerous human diseases. I describe here a novel strategy for systematically identifying budding yeast mutants with elevated levels of DNA damage foci, which represent hubs of DNA damage and repair. A previous study manually scored foc...
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| Language: | en_ca |
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2011
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| Online Access: | http://hdl.handle.net/1807/29544 |