Predicting Treatment Response and the Role of the ISG15/USP18 Ubiquitin-like Signaling Pathway in Hepatitis C Viral Infection
Hepatitis C Virus (HCV) infects 170 million people worldwide. The current treatment regimen, which is combination therapy with pegylated interferon (PegIFN) and Ribavirin (Rib), cures only 50% of the patients infected with the most prevalent HCV genotype. Therefore, there is a pressing need to unde...
Main Author: | Chen, Limin |
---|---|
Other Authors: | Edwards, Aled M. |
Language: | en_ca |
Published: |
2010
|
Subjects: | |
Online Access: | http://hdl.handle.net/1807/26137 |
Similar Items
-
Predicting Treatment Response and the Role of the ISG15/USP18 Ubiquitin-like Signaling Pathway in Hepatitis C Viral Infection
by: Chen, Limin
Published: (2010) -
Strategies to Target ISG15 and USP18 Toward Therapeutic Applications
by: Daniel Jiménez Fernández, et al.
Published: (2020-01-01) -
Emerging Roles of USP18: From Biology to Pathophysiology
by: Ji An Kang, et al.
Published: (2020-09-01) -
Insights on type I IFN signaling and regulation : studies of disease-associated TYK2 variants and of the negative regulators USP18/ISG15
by: Li, Zhi
Published: (2017) -
Antiviral Properties of ISG15
by: Deborah J. Lenschow
Published: (2010-09-01)