Assessment of the Functional Role of the NTR Domain of Complement Component C3 using a Homologous Dmain Exchange Approach
The complement system plays an important role in innate and adaptive immunity. Central to all complement activities is the function of complement component 3 (C3). C3 contains a C-terminal extension of ~150 residues known as the NTR (or C345C) domain. To address the role of the NTR domain in binding...
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| Language: | en_ca |
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2010
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| Online Access: | http://hdl.handle.net/1807/25901 |