Cardiac Glycosides, a Novel Treatment for Neuroblastoma: Efficacy and Mechanism

In an attempt to identify agents that specifically target neuroblastoma (NB) tumour-initiating cells (TIC) we performed drug screens using libraries of bioactive compounds. Cardiac glycosides (CGs) were the largest class of drugs identified with antitumour activity. At high CG doses inhibitory effec...

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Bibliographic Details
Main Author: De Gouveia, Paulo
Other Authors: Irwin, Meredith
Language:en_ca
Published: 2010
Subjects:
Online Access:http://hdl.handle.net/1807/25547