Investigation of the Mechanisms of Drug-induced Agranulocytosis

Idiosyncratic drug reactions (IDRs) are unpredictable adverse drug reactions. Their exact mechanisms are unknown but most appear to be immune-mediated. Mechanistic studies require valid animal models, but there are very few available and none for the study of drug-induced agranulocytosis. Thus, t...

Full description

Bibliographic Details
Main Author: Ip, Julia Ring Tin
Other Authors: Uetrecht, Jack
Language:en_ca
Published: 2009
Subjects:
Online Access:http://hdl.handle.net/1807/19043