Endoplasmic Reticulum Stress in Pancreatic Beta-cells
Endoplasmic reticulum (ER) stress has been implicated in pancreatic beta-cell loss contributing to diabetes mellitus, however the molecular mechanisms of ER stress-induced apoptosis are unclear. In the first project of this thesis, the contribution of ER stress in proinflammatory cytokine-mediated...
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| Language: | en_ca |
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2009
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| Online Access: | http://hdl.handle.net/1807/18337 |