Herramientas de cribado virtual aplicadas a inhibidores de entrada del VIH. Diseño de nuevos compuestos anti-VIH

Herramientas de cribado virtual aplicadas a inhibidores de entrada del VIH. Diseño de nuevos compuestos anti-VIH

Els inhibidors d'entrada del VIH han sorgit recentment com una nova generació de fàrmacs antiretrovirals, els quals bloquegen la unió del virus als co-receptors de membrana CXCR4 i CCR5. S'han desenvolupat diverses molècules petites antagonistes d'aquests co-receptors, algunes de les...

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Bibliographic Details
Main Author:	Pérez Nueno, Violeta Isabel
Other Authors:	Teixidó Closa, Jordi
Format:	Doctoral Thesis
Language:	Spanish
Published:	Universitat Ramon Llull 2009
Subjects:	de novo design interaction fingerprint similarity search shape matching pharmacophore docking CXCR4/CCR5 inhibitors HIV virtual screening diseño de novo fingerprint de interacción búsqueda de similitud farmacóforo inhibidores de CXCR4/CCR5 VIH cribado virtual recerca de similitud fingerprint d'interacció disseny de novo farmacòfor inhibidors de CXCR4/CCR5 cribatge virtual Química i Enginyeria Química 547
Online Access:	http://hdl.handle.net/10803/9311

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