Combined use of NMR and computational tools for fragment based drug discovery targeting protein-protein interactions VEGF protein surface recognition as a case study
The capacity of proteins to interact with each other rests at the core of biology. Given the ubiquitous nature of these interactions they have attracted the attention of scientists for the development of inhibitors or biochemical tools.The use of biologics to target protein-protein interfaces is rel...
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| Format: | Doctoral Thesis |
| Language: | English |
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Universitat de Barcelona
2013
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| Online Access: | http://hdl.handle.net/10803/123711 |