The effects of buffer molarity, agitation rate and mesh size on verapamil release from modified release mini-tablets using USP Apparatus 3

The effects of agitation rate, buffer molarity,and mesh size on the dissolution rate of verapamil hydrochloride from sustained release matrix tablets were studied using USP Apparatus 3. Eudragit® and Carbopol® were used as rate-retarding polymers in tablets prepared by wet granulation.The study was...

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Main Authors: Khamanga, S.M.M., Walker, R.B.
Format: Others
Published: 2007
Subjects:
Online Access:http://eprints.ru.ac.za/735/1/The_effects_of_buffer_molarity%2C_agitation_rate_and_mesh_size_on_verapamil_release_from_MR_mini-tablets_using_USP_Apparatus_III.pdf
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spelling ndltd-Rhodes-oai-eprints.ru.ac.za-7352011-12-13T15:24:56Z The effects of buffer molarity, agitation rate and mesh size on verapamil release from modified release mini-tablets using USP Apparatus 3 Khamanga, S.M.M. Walker, R.B. Subjects to be assigned The effects of agitation rate, buffer molarity,and mesh size on the dissolution rate of verapamil hydrochloride from sustained release matrix tablets were studied using USP Apparatus 3. Eudragit® and Carbopol® were used as rate-retarding polymers in tablets prepared by wet granulation.The study was conducted to determine whether the drugs exhibit similar release characteristics when tested under the same dissolution conditions. It was found that the dissolution rate of verapamil hydrochloride was affected by the variables assessed in these studies. 2007-05 Article PeerReviewed application/pdf http://eprints.ru.ac.za/735/1/The_effects_of_buffer_molarity%2C_agitation_rate_and_mesh_size_on_verapamil_release_from_MR_mini-tablets_using_USP_Apparatus_III.pdf http://www.dissolutiontech.com/DTresour/200705Articles/DT200705_A02.pdf Khamanga, S.M.M. and Walker, R.B. (2007) The effects of buffer molarity, agitation rate and mesh size on verapamil release from modified release mini-tablets using USP Apparatus 3. Dissolution Technologies, 14 (2). pp. 19-23. ISSN 1521-298X http://eprints.ru.ac.za/735/
collection NDLTD
format Others
sources NDLTD
topic Subjects to be assigned
spellingShingle Subjects to be assigned
Khamanga, S.M.M.
Walker, R.B.
The effects of buffer molarity, agitation rate and mesh size on verapamil release from modified release mini-tablets using USP Apparatus 3
description The effects of agitation rate, buffer molarity,and mesh size on the dissolution rate of verapamil hydrochloride from sustained release matrix tablets were studied using USP Apparatus 3. Eudragit® and Carbopol® were used as rate-retarding polymers in tablets prepared by wet granulation.The study was conducted to determine whether the drugs exhibit similar release characteristics when tested under the same dissolution conditions. It was found that the dissolution rate of verapamil hydrochloride was affected by the variables assessed in these studies.
author Khamanga, S.M.M.
Walker, R.B.
author_facet Khamanga, S.M.M.
Walker, R.B.
author_sort Khamanga, S.M.M.
title The effects of buffer molarity, agitation rate and mesh size on verapamil release from modified release mini-tablets using USP Apparatus 3
title_short The effects of buffer molarity, agitation rate and mesh size on verapamil release from modified release mini-tablets using USP Apparatus 3
title_full The effects of buffer molarity, agitation rate and mesh size on verapamil release from modified release mini-tablets using USP Apparatus 3
title_fullStr The effects of buffer molarity, agitation rate and mesh size on verapamil release from modified release mini-tablets using USP Apparatus 3
title_full_unstemmed The effects of buffer molarity, agitation rate and mesh size on verapamil release from modified release mini-tablets using USP Apparatus 3
title_sort effects of buffer molarity, agitation rate and mesh size on verapamil release from modified release mini-tablets using usp apparatus 3
publishDate 2007
url http://eprints.ru.ac.za/735/1/The_effects_of_buffer_molarity%2C_agitation_rate_and_mesh_size_on_verapamil_release_from_MR_mini-tablets_using_USP_Apparatus_III.pdf
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