The effects of buffer molarity, agitation rate and mesh size on verapamil release from modified release mini-tablets using USP Apparatus 3
The effects of agitation rate, buffer molarity,and mesh size on the dissolution rate of verapamil hydrochloride from sustained release matrix tablets were studied using USP Apparatus 3. Eudragit® and Carbopol® were used as rate-retarding polymers in tablets prepared by wet granulation.The study was...
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ndltd-Rhodes-oai-eprints.ru.ac.za-7352011-12-13T15:24:56Z The effects of buffer molarity, agitation rate and mesh size on verapamil release from modified release mini-tablets using USP Apparatus 3 Khamanga, S.M.M. Walker, R.B. Subjects to be assigned The effects of agitation rate, buffer molarity,and mesh size on the dissolution rate of verapamil hydrochloride from sustained release matrix tablets were studied using USP Apparatus 3. Eudragit® and Carbopol® were used as rate-retarding polymers in tablets prepared by wet granulation.The study was conducted to determine whether the drugs exhibit similar release characteristics when tested under the same dissolution conditions. It was found that the dissolution rate of verapamil hydrochloride was affected by the variables assessed in these studies. 2007-05 Article PeerReviewed application/pdf http://eprints.ru.ac.za/735/1/The_effects_of_buffer_molarity%2C_agitation_rate_and_mesh_size_on_verapamil_release_from_MR_mini-tablets_using_USP_Apparatus_III.pdf http://www.dissolutiontech.com/DTresour/200705Articles/DT200705_A02.pdf Khamanga, S.M.M. and Walker, R.B. (2007) The effects of buffer molarity, agitation rate and mesh size on verapamil release from modified release mini-tablets using USP Apparatus 3. Dissolution Technologies, 14 (2). pp. 19-23. ISSN 1521-298X http://eprints.ru.ac.za/735/ |
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Subjects to be assigned Khamanga, S.M.M. Walker, R.B. The effects of buffer molarity, agitation rate and mesh size on verapamil release from modified release mini-tablets using USP Apparatus 3 |
description |
The effects of agitation rate, buffer molarity,and mesh size on the dissolution rate of verapamil hydrochloride from sustained release matrix tablets were studied using USP Apparatus 3. Eudragit® and Carbopol® were used as rate-retarding polymers in tablets prepared by wet granulation.The study was conducted to determine whether the drugs exhibit similar release characteristics when tested under the same dissolution conditions. It was found that the dissolution rate of verapamil hydrochloride was affected by the variables assessed in these studies. |
author |
Khamanga, S.M.M. Walker, R.B. |
author_facet |
Khamanga, S.M.M. Walker, R.B. |
author_sort |
Khamanga, S.M.M. |
title |
The effects of buffer molarity, agitation rate and mesh size on verapamil release from modified release mini-tablets using USP Apparatus 3 |
title_short |
The effects of buffer molarity, agitation rate and mesh size on verapamil release from modified release mini-tablets using USP Apparatus 3 |
title_full |
The effects of buffer molarity, agitation rate and mesh size on verapamil release from modified release mini-tablets using USP Apparatus 3 |
title_fullStr |
The effects of buffer molarity, agitation rate and mesh size on verapamil release from modified release mini-tablets using USP Apparatus 3 |
title_full_unstemmed |
The effects of buffer molarity, agitation rate and mesh size on verapamil release from modified release mini-tablets using USP Apparatus 3 |
title_sort |
effects of buffer molarity, agitation rate and mesh size on verapamil release from modified release mini-tablets using usp apparatus 3 |
publishDate |
2007 |
url |
http://eprints.ru.ac.za/735/1/The_effects_of_buffer_molarity%2C_agitation_rate_and_mesh_size_on_verapamil_release_from_MR_mini-tablets_using_USP_Apparatus_III.pdf |
work_keys_str_mv |
AT khamangasmm theeffectsofbuffermolarityagitationrateandmeshsizeonverapamilreleasefrommodifiedreleaseminitabletsusinguspapparatus3 AT walkerrb theeffectsofbuffermolarityagitationrateandmeshsizeonverapamilreleasefrommodifiedreleaseminitabletsusinguspapparatus3 AT khamangasmm effectsofbuffermolarityagitationrateandmeshsizeonverapamilreleasefrommodifiedreleaseminitabletsusinguspapparatus3 AT walkerrb effectsofbuffermolarityagitationrateandmeshsizeonverapamilreleasefrommodifiedreleaseminitabletsusinguspapparatus3 |
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1716389471011733504 |