Self-Administration Results in Dynamic Changes in DNA Methylation of the Dorsal Medial Prefrontal Cortex throughout Forced Abstinence, and after Re-exposure to Cues

<p> Similar to the pattern observed in people with substance abuse disorders, laboratory animals will exhibit escalation of cocaine intake when the drug is readily available and will exhibit increased drug-seeking behaviors after long periods of abstinence. Additionally, there are long term ch...

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Bibliographic Details
Main Author: Ploense, Kyle Lawrence
Language:EN
Published: University of California, Santa Barbara 2018
Subjects:
Online Access:http://pqdtopen.proquest.com/#viewpdf?dispub=10689933