Macrolide resistance mechanisms in Enterobacteriaceae: Focus on azithromycin
From its introduction in 1952 onwards, the clinical use of macrolides has been steadily increasing, both in human and veterinary medicine. Although initially designed to the treatment of Grampositive microorganisms, this antimicrobial family has also been used to treat specific Gram-negative bact...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Taylor & Francis
2016
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| Online Access: | 1. Gomes C, Martínez-puchol S, Palma N, Horna G, Ruiz-roldán L, Pons MJ, et al. Critical Reviews in Microbiology Macrolide resistance mechanisms in Enterobacteriaceae : Focus on azithromycin Macrolide resistance mechanisms in Enterobacteriaceae : Focus on azithromycin. Crit Rev Microbiol [Internet]. Informa Healthcare USA, Inc; 2016;0(0):000. Available from: http://dx.doi.org/10.3109/1040841X.2015.1136261 http://hdl.handle.net/10757/620710 http://repositorioacademico.upc.edu.pe/upc/handle/10757/620710 |
| Summary: | From its introduction in 1952 onwards, the clinical use of macrolides has been steadily increasing,
both in human and veterinary medicine. Although initially designed to the treatment of Grampositive
microorganisms, this antimicrobial family has also been used to treat specific Gram-negative
bacteria. Some of them, as azithromycin, are considered in the armamentarium against
Enterobacteriaceae infections. However, the facility that this bacterial genus has to gain or
develop mechanisms of antibiotic resistance may compromise the future usefulness of these antibiotics
to fight against Enterobacteriaceae infections. The present review is focused on the mechanisms
of macrolide resistance, currently described in Enterobacteriaceae. |
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