Antibiotic resistance in Bartonella bacilliformis clinical isolates from an endemic area of Peru

Bartonella bacilliformis is a facultative, intracellular, aerobic, Gram-negative coccobacillus causing the so-called Carrión's disease, a human infection endemic to specific areas mainly inhabited by low-income communities of Peru but also present in other Andean communities. It is considered a...

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Bibliographic Details
Main Authors: Silva Caso, Wilmer, J. Ruiz, Del Valle Mendoza, Juana, Pons, Maria J
Format: Article
Language:English
Published: Elsevier B.V. 2015
Subjects:
Online Access:Silva-Caso W, Pons MJ, Ruiz J, del Valle-Mendoza J, Antibiotic resistance in Bartonella bacilliformis clinical isolates from an endemic area of Peru, Journal of Global Antimicrobial Resistance (2010), http://dx.doi.org/10.1016/j.jgar.2015.05.004
http://hdl.handle.net/10757/579762
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Summary:Bartonella bacilliformis is a facultative, intracellular, aerobic, Gram-negative coccobacillus causing the so-called Carrión's disease, a human infection endemic to specific areas mainly inhabited by low-income communities of Peru but also present in other Andean communities. It is considered a truly neglected tropical disease and is transmitted through the bite of female sandflies of the genus Lutzomyia [1]. Carrión's disease has two different clinical presentations; an initial febrile and haemolytic anaemia phase, known as Oroya fever, which has a mortality rate ranging from 44% to 88% in untreated patients; and a second phase characterised by the development of dermal eruptions known as Peruvian wart [1,2].  === The study was supported by internal funds from the Universidad Peruana de Ciencias Aplicadas (Lima, Peru); by a grant from the Instituto de Salud Carlos III, Spain [PI11/00983], which included FEDER funds; by the UBS Optimus Foundation; and by Generalitat de Catalunya, Departament d’Universitats, Recerca i Societat de la Informació [2014 SGR 26]. MJP has received a postdoctoral fellowship from CONCYTEC/FONDECYT. JR has received a fellowship from the program I3 of the ISCIII [grant no. CES11/012]. === Revisión por pares