The aging-related gene expression of a component of Sp100-rs in adipocytes may correlate to the redistribution of white adipocyte tissue to various organs in <i>Mus musculus</i>
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Wittenberg University Honors Theses / OhioLINK
2013
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| Online Access: | http://rave.ohiolink.edu/etdc/view?acc_num=wuhonors1398960853 |
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ndltd-OhioLink-oai-etd.ohiolink.edu-wuhonors13989608532021-08-03T06:24:36Z The aging-related gene expression of a component of Sp100-rs in adipocytes may correlate to the redistribution of white adipocyte tissue to various organs in <i>Mus musculus</i> Heepke, Wendroth Biochemistry Molecular Biology Genetics Aging aging mice Csprs genetics The component of an Sp100-rs (<i>Csprs</i>) gene has shown an aging-related increase in expression in mouse tissues, including the heart, kidney, and fats. While the up-regulation is not always significant, the trend of increased expression suggests that <i>Csprs</i> may be used as a biomarker for aging. <i>Csprs</i> seems to be associated primarily with adipose tissue, and its expression usually correlates to high amounts of adiponectin. Furthermore, within white adipose tissue, <i>Csprs</i> is mostly expressed in adipocytes but not in stromal vascular cells, suggesting that the gene may, in fact, be adipose-specific. Therefore, the aging-related increase of <i>Csprs</i> in tissues like the heart and kidney could be related to the fat accumulation in these tissues with age. This suggests a link between <i>Csprs</i> expression, aging, and development of various aging-related diseases such as diabetes and coronary heart disease. 2013 English text Wittenberg University Honors Theses / OhioLINK http://rave.ohiolink.edu/etdc/view?acc_num=wuhonors1398960853 http://rave.ohiolink.edu/etdc/view?acc_num=wuhonors1398960853 unrestricted This thesis or dissertation is protected by copyright: all rights reserved. It may not be copied or redistributed beyond the terms of applicable copyright laws. |
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NDLTD |
| language |
English |
| sources |
NDLTD |
| topic |
Biochemistry Molecular Biology Genetics Aging aging mice Csprs genetics |
| spellingShingle |
Biochemistry Molecular Biology Genetics Aging aging mice Csprs genetics Heepke, Wendroth The aging-related gene expression of a component of Sp100-rs in adipocytes may correlate to the redistribution of white adipocyte tissue to various organs in <i>Mus musculus</i> |
| author |
Heepke, Wendroth |
| author_facet |
Heepke, Wendroth |
| author_sort |
Heepke, Wendroth |
| title |
The aging-related gene expression of a component of Sp100-rs in adipocytes may correlate to the redistribution of white adipocyte tissue to various organs in <i>Mus musculus</i> |
| title_short |
The aging-related gene expression of a component of Sp100-rs in adipocytes may correlate to the redistribution of white adipocyte tissue to various organs in <i>Mus musculus</i> |
| title_full |
The aging-related gene expression of a component of Sp100-rs in adipocytes may correlate to the redistribution of white adipocyte tissue to various organs in <i>Mus musculus</i> |
| title_fullStr |
The aging-related gene expression of a component of Sp100-rs in adipocytes may correlate to the redistribution of white adipocyte tissue to various organs in <i>Mus musculus</i> |
| title_full_unstemmed |
The aging-related gene expression of a component of Sp100-rs in adipocytes may correlate to the redistribution of white adipocyte tissue to various organs in <i>Mus musculus</i> |
| title_sort |
aging-related gene expression of a component of sp100-rs in adipocytes may correlate to the redistribution of white adipocyte tissue to various organs in <i>mus musculus</i> |
| publisher |
Wittenberg University Honors Theses / OhioLINK |
| publishDate |
2013 |
| url |
http://rave.ohiolink.edu/etdc/view?acc_num=wuhonors1398960853 |
| work_keys_str_mv |
AT heepkewendroth theagingrelatedgeneexpressionofacomponentofsp100rsinadipocytesmaycorrelatetotheredistributionofwhiteadipocytetissuetovariousorgansinimusmusculusi AT heepkewendroth agingrelatedgeneexpressionofacomponentofsp100rsinadipocytesmaycorrelatetotheredistributionofwhiteadipocytetissuetovariousorgansinimusmusculusi |
| _version_ |
1719436637513973760 |