Single-cell transcriptomic analysis of vascular progenitors and the roles of Vegf signaling and Ets1 in vascular development

Single-cell transcriptomic analysis of vascular progenitors and the roles of Vegf signaling and Ets1 in vascular development

Bibliographic Details
Main Author: Casie Chetty, David S.
Language:English
Published: University of Cincinnati / OhioLINK 2020
Subjects:
Cognitive Psychology
Developmental Biology
Vasculogenesis
Development
ETS factors
Angiogenesis
Etv2
VEGF
Online Access:http://rave.ohiolink.edu/etdc/view?acc_num=ucin159326667315738
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spelling ndltd-OhioLink-oai-etd.ohiolink.edu-ucin1593266673157382021-08-03T07:15:31Z Single-cell transcriptomic analysis of vascular progenitors and the roles of Vegf signaling and Ets1 in vascular development Casie Chetty, David S. Cognitive Psychology Developmental Biology Vasculogenesis Development ETS factors Angiogenesis Etv2 VEGF The formation of a functional vascular system is required for proper embryonic development in all vertebrates. Being one of the first organ systems to form during embryogenesis, ¬the cardiovascular system, comprising the heart, arteries, veins and capillaries, transports nutrients, oxygen, metabolites, waste, immune cells and hormones throughout the body. Thus, the formation of organ systems during development and subsequent maintenance throughout life is reliant upon a normal functional vascular system. This dissertation focuses on the molecular mechanisms that govern vascular development in zebrafish embryos. We utilize zebrafish embryos due to their rapid development, optical transparency and high amenability to genetic manipulation. 2020-09-27 English text University of Cincinnati / OhioLINK http://rave.ohiolink.edu/etdc/view?acc_num=ucin159326667315738 http://rave.ohiolink.edu/etdc/view?acc_num=ucin159326667315738 unrestricted This thesis or dissertation is protected by copyright: all rights reserved. It may not be copied or redistributed beyond the terms of applicable copyright laws.
collection NDLTD
language English
sources NDLTD
topic Cognitive Psychology
Developmental Biology
Vasculogenesis
Development
ETS factors
Angiogenesis
Etv2
VEGF
spellingShingle Cognitive Psychology
Developmental Biology
Vasculogenesis
Development
ETS factors
Angiogenesis
Etv2
VEGF
Casie Chetty, David S.
Single-cell transcriptomic analysis of vascular progenitors and the roles of Vegf signaling and Ets1 in vascular development
author Casie Chetty, David S.
author_facet Casie Chetty, David S.
author_sort Casie Chetty, David S.
title Single-cell transcriptomic analysis of vascular progenitors and the roles of Vegf signaling and Ets1 in vascular development
title_short Single-cell transcriptomic analysis of vascular progenitors and the roles of Vegf signaling and Ets1 in vascular development
title_full Single-cell transcriptomic analysis of vascular progenitors and the roles of Vegf signaling and Ets1 in vascular development
title_fullStr Single-cell transcriptomic analysis of vascular progenitors and the roles of Vegf signaling and Ets1 in vascular development
title_full_unstemmed Single-cell transcriptomic analysis of vascular progenitors and the roles of Vegf signaling and Ets1 in vascular development
title_sort single-cell transcriptomic analysis of vascular progenitors and the roles of vegf signaling and ets1 in vascular development
publisher University of Cincinnati / OhioLINK
publishDate 2020
url http://rave.ohiolink.edu/etdc/view?acc_num=ucin159326667315738
work_keys_str_mv AT casiechettydavids singlecelltranscriptomicanalysisofvascularprogenitorsandtherolesofvegfsignalingandets1invasculardevelopment
_version_ 1719457698664153088

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