Treatment Trends for Youth-Onset Type 2 Diabetes Mellitus in the United States

Treatment Trends for Youth-Onset Type 2 Diabetes Mellitus in the United States

Bibliographic Details
Main Author: Damachi, Udim T.
Language:English
Published: University of Cincinnati / OhioLINK 2020
Subjects:
Pharmaceuticals
Youth-onset T2DM
Treatment
Antidiabetics
Diabetes type 2
Management
Adolecents
Online Access:http://rave.ohiolink.edu/etdc/view?acc_num=ucin1592171636938994
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spelling ndltd-OhioLink-oai-etd.ohiolink.edu-ucin15921716369389942021-11-02T05:17:54Z Treatment Trends for Youth-Onset Type 2 Diabetes Mellitus in the United States Damachi, Udim T. Pharmaceuticals Youth-onset T2DM Treatment Antidiabetics Diabetes type 2 Management Adolecents Background:Type 2 diabetes mellitus (T2DM) is a chronic, progressive disease characterized by insulin resistance, glucose intolerance, and hyperglycemia. Over the years, the prevalence of T2DM has increased in children and adolescents, and it's associated with a rapid decline in beta-cell function and complications. There is limited literature that examines treatment trends and racial disparities in youths with T2DM. Goal and aims:The aim of this study is to describe the patient characteristics of youth-onset T2DM; to determine pharmacological and non-pharmacological treatment trends in the management of youth-onset T2DM and to examine the disparities in the treatment of youth-onset T2DM among different racial and ethnic groups. Methods:This was a retrospective cross-sectional study that analyzed the National Ambulatory Medical Care Survey (NAMCS) and National Hospital Ambulatory Medical Care Survey (NHAMCS) from 2006-2017. Patient visits with T2DM were identified using the International Classification (ICD) code and the binary question in the NAMCS/NHAMCS survey, “Does patient now have Diabetes mellitus Type 2”. Descriptive statistics, chi-squared tests, and weighted logistic regressions were carried out to assess treatment patterns and disparities in treatment among different racial and ethnic groups. Results:Patient visits were mostly between the ages of 15-19 years (62.6%) and female patients represented more than half of the study population (59.8%). The majority of the visits were non-Hispanics (83.9%), white (64.3%) and from the southern region of the United States (48.8%). The percentage of patient visits that received an antidiabetic drug decreased from 79.9% in 2006-2011 to 46.5% in 2012-2017 (P=0.0007), and the percentage of patients who did not receive treatment increased from 12.6% to 41.3% in the same time period (P=0.0002). For patient visits with non-pharmacological intervention, the percentage decreased from 38.5% in 2006-2011 to 33.1% in 2012-2017 (P=0.6917). Racial disparities were observed, non-Hispanic blacks were more likely to receive a lifestyle intervention when compared to other racial/ethnic groups(P=0.024), and whites were more likely to receive only an antidiabetic without lifestyle interventions when compared to other races(P=0.045).Conclusion: 2020-10-29 English text University of Cincinnati / OhioLINK http://rave.ohiolink.edu/etdc/view?acc_num=ucin1592171636938994 http://rave.ohiolink.edu/etdc/view?acc_num=ucin1592171636938994 unrestricted This thesis or dissertation is protected by copyright: all rights reserved. It may not be copied or redistributed beyond the terms of applicable copyright laws.
collection NDLTD
language English
sources NDLTD
topic Pharmaceuticals
Youth-onset T2DM
Treatment
Antidiabetics
Diabetes type 2
Management
Adolecents
spellingShingle Pharmaceuticals
Youth-onset T2DM
Treatment
Antidiabetics
Diabetes type 2
Management
Adolecents
Damachi, Udim T.
Treatment Trends for Youth-Onset Type 2 Diabetes Mellitus in the United States
author Damachi, Udim T.
author_facet Damachi, Udim T.
author_sort Damachi, Udim T.
title Treatment Trends for Youth-Onset Type 2 Diabetes Mellitus in the United States
title_short Treatment Trends for Youth-Onset Type 2 Diabetes Mellitus in the United States
title_full Treatment Trends for Youth-Onset Type 2 Diabetes Mellitus in the United States
title_fullStr Treatment Trends for Youth-Onset Type 2 Diabetes Mellitus in the United States
title_full_unstemmed Treatment Trends for Youth-Onset Type 2 Diabetes Mellitus in the United States
title_sort treatment trends for youth-onset type 2 diabetes mellitus in the united states
publisher University of Cincinnati / OhioLINK
publishDate 2020
url http://rave.ohiolink.edu/etdc/view?acc_num=ucin1592171636938994
work_keys_str_mv AT damachiudimt treatmenttrendsforyouthonsettype2diabetesmellitusintheunitedstates
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