Better diagnosis of coronary artery disease using combined trans-lesional hemodynamics and anatomical information

Better diagnosis of coronary artery disease using combined trans-lesional hemodynamics and anatomical information

Bibliographic Details
Main Author: Peelukhana, Srikara Vishwanath
Language:English
Published: University of Cincinnati / OhioLINK 2014
Subjects:
Individual and Family Studies
Mechanical Engineering
stenosis
mechanical engineering
Online Access:http://rave.ohiolink.edu/etdc/view?acc_num=ucin1407406861
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spelling ndltd-OhioLink-oai-etd.ohiolink.edu-ucin14074068612021-08-03T06:26:57Z Better diagnosis of coronary artery disease using combined trans-lesional hemodynamics and anatomical information Peelukhana, Srikara Vishwanath Individual and Family Studies Mechanical Engineering stenosis mechanical engineering Invasive diagnosis of coronary artery disease utilizes either anatomical or functional measurements. The objective of this dissertation is to improve the diagnosis of coronary artery disease such as epicardial stenosis and microvascular disease using combined anatomical (%area stenosis: %AS) and functional (pressure and flow) parameter, lesion flow coefficient (LFC). The LFC is defined as the ratio of %AS to the square root of the ratio of the pressure drop across the stenosis to the dynamic pressure in the throat region). The hypothesis is that the LFC can better delineate the contributions of epicardial stenosis and microvascular disease, under clinical scenario. To test the hypothesis, three Specific Aims are formulated: 1. 2014-10-10 English text University of Cincinnati / OhioLINK http://rave.ohiolink.edu/etdc/view?acc_num=ucin1407406861 http://rave.ohiolink.edu/etdc/view?acc_num=ucin1407406861 unrestricted This thesis or dissertation is protected by copyright: all rights reserved. It may not be copied or redistributed beyond the terms of applicable copyright laws.
collection NDLTD
language English
sources NDLTD
topic Individual and Family Studies
Mechanical Engineering
stenosis
mechanical engineering
spellingShingle Individual and Family Studies
Mechanical Engineering
stenosis
mechanical engineering
Peelukhana, Srikara Vishwanath
Better diagnosis of coronary artery disease using combined trans-lesional hemodynamics and anatomical information
author Peelukhana, Srikara Vishwanath
author_facet Peelukhana, Srikara Vishwanath
author_sort Peelukhana, Srikara Vishwanath
title Better diagnosis of coronary artery disease using combined trans-lesional hemodynamics and anatomical information
title_short Better diagnosis of coronary artery disease using combined trans-lesional hemodynamics and anatomical information
title_full Better diagnosis of coronary artery disease using combined trans-lesional hemodynamics and anatomical information
title_fullStr Better diagnosis of coronary artery disease using combined trans-lesional hemodynamics and anatomical information
title_full_unstemmed Better diagnosis of coronary artery disease using combined trans-lesional hemodynamics and anatomical information
title_sort better diagnosis of coronary artery disease using combined trans-lesional hemodynamics and anatomical information
publisher University of Cincinnati / OhioLINK
publishDate 2014
url http://rave.ohiolink.edu/etdc/view?acc_num=ucin1407406861
work_keys_str_mv AT peelukhanasrikaravishwanath betterdiagnosisofcoronaryarterydiseaseusingcombinedtranslesionalhemodynamicsandanatomicalinformation
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