A Systematic Review of Vitamin D Deficiency in Pregnancy in India and its Impact on Maternal and Fetal Outcomes
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ndltd-OhioLink-oai-etd.ohiolink.edu-ucin13972352092021-08-03T06:23:34Z A Systematic Review of Vitamin D Deficiency in Pregnancy in India and its Impact on Maternal and Fetal Outcomes Tasset, Julia L. Public Health Vitamin D Pregnancy India Background: Vitamin D is a hormone that has long been known to play a crucial role in bone mineralization. However, it has recently been implicated in a variety of conditions,such as cancer, respiratory illnesses, immune system modification, and muscle weakness [1]. With a growing body of evidence that, even at tropical latitudes, pregnant women are particularly at risk for vitamin D deficiency, many researchers have begun to clarify the prevalence of this condition around the world, its relationship with a variety of health outcomes, and the most effective ways to combat deficiency.Objective: To summarize the body of evidence concerning vitamin D deficiency in India, risk factors, and itsassociation with maternal and fetal health outcomes. Methods: The electronic databases PubMed, Scopus, and the Cochrane Library were searched using the keywords “vitamin D” and “India” and “pregnancy.” A systematic review was applied to all observational and interventional studies assessing serum 25- hydroxyvitamin D (25(OH)D) levels during pregnancy, risk factors, and outcomes. Results: Eleven studies met inclusion criteria and quality control testing. Studies report that 66-98% of pregnant Indian women have vitamin D levels below 50 nmol/L, the standard for deficiency adopted by many studies. Mean levels of 25(OH)D ranged from 21.9-81.7 nmol/L. Maternal vitamin D level was correlated in several studies with season, but there was little consensus regarding associated health outcomes. Conclusions: Vitamin D deficiency is common in India in pregnant women but conclusions regarding risk factors and adverse outcomes are unclear. Additional studies with larger sample sizes analyzing risk factors for deficiency and adverse outcomes are necessary. 2014-10-27 English text University of Cincinnati / OhioLINK http://rave.ohiolink.edu/etdc/view?acc_num=ucin1397235209 http://rave.ohiolink.edu/etdc/view?acc_num=ucin1397235209 unrestricted This thesis or dissertation is protected by copyright: all rights reserved. It may not be copied or redistributed beyond the terms of applicable copyright laws. |
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NDLTD |
language |
English |
sources |
NDLTD |
topic |
Public Health Vitamin D Pregnancy India |
spellingShingle |
Public Health Vitamin D Pregnancy India Tasset, Julia L. A Systematic Review of Vitamin D Deficiency in Pregnancy in India and its Impact on Maternal and Fetal Outcomes |
author |
Tasset, Julia L. |
author_facet |
Tasset, Julia L. |
author_sort |
Tasset, Julia L. |
title |
A Systematic Review of Vitamin D Deficiency in Pregnancy in India and its Impact on Maternal and Fetal Outcomes |
title_short |
A Systematic Review of Vitamin D Deficiency in Pregnancy in India and its Impact on Maternal and Fetal Outcomes |
title_full |
A Systematic Review of Vitamin D Deficiency in Pregnancy in India and its Impact on Maternal and Fetal Outcomes |
title_fullStr |
A Systematic Review of Vitamin D Deficiency in Pregnancy in India and its Impact on Maternal and Fetal Outcomes |
title_full_unstemmed |
A Systematic Review of Vitamin D Deficiency in Pregnancy in India and its Impact on Maternal and Fetal Outcomes |
title_sort |
systematic review of vitamin d deficiency in pregnancy in india and its impact on maternal and fetal outcomes |
publisher |
University of Cincinnati / OhioLINK |
publishDate |
2014 |
url |
http://rave.ohiolink.edu/etdc/view?acc_num=ucin1397235209 |
work_keys_str_mv |
AT tassetjulial asystematicreviewofvitaminddeficiencyinpregnancyinindiaanditsimpactonmaternalandfetaloutcomes AT tassetjulial systematicreviewofvitaminddeficiencyinpregnancyinindiaanditsimpactonmaternalandfetaloutcomes |
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