Using Agent-based Modeling and Simulation to Study the Structural Behavior of DNA

Bibliographic Details
Main Author: Ahmed, Mohammad Nasar
Language:English
Published: University of Cincinnati / OhioLINK 2011
Subjects:
Online Access:http://rave.ohiolink.edu/etdc/view?acc_num=ucin1318608371
id ndltd-OhioLink-oai-etd.ohiolink.edu-ucin1318608371
record_format oai_dc
spelling ndltd-OhioLink-oai-etd.ohiolink.edu-ucin13186083712021-08-03T06:15:05Z Using Agent-based Modeling and Simulation to Study the Structural Behavior of DNA Ahmed, Mohammad Nasar Computer Engineering Agent-based modeling and simulation (ABMS) is a powerful tool for modeling phenomena at the molecular level. ABMS can be applied to model a system that can simulate the structural behavior of DNA. The system we intend to model needs to be powerful enough to simulate the well-known laboratory experiments on DNA by Adelman. This system should also be able to simulate the properties of emerging nanodevices. The system must demonstrate the basic structural behavior of DNA such as synthesis of double stranded DNA, formation of branched structures and separation of double stranded DNA. The system aimed to design must be able to be extended to be used to model the DNA self-assembly required in the process of fabrication of nanocircuits. Here we describe our work on developing basic building blocks for the system that can implement complex DNA models such as Adelman’s experiment and the experiments we conducted to validate our work. The experiments were chosen to cover the basic behavioral aspects of DNA such as synthesis of double stranded DNA, time taken for synthesizing DNA and separation of double stranded DNA. 2011 English text University of Cincinnati / OhioLINK http://rave.ohiolink.edu/etdc/view?acc_num=ucin1318608371 http://rave.ohiolink.edu/etdc/view?acc_num=ucin1318608371 unrestricted This thesis or dissertation is protected by copyright: some rights reserved. It is licensed for use under a Creative Commons license. Specific terms and permissions are available from this document's record in the OhioLINK ETD Center.
collection NDLTD
language English
sources NDLTD
topic Computer Engineering
spellingShingle Computer Engineering
Ahmed, Mohammad Nasar
Using Agent-based Modeling and Simulation to Study the Structural Behavior of DNA
author Ahmed, Mohammad Nasar
author_facet Ahmed, Mohammad Nasar
author_sort Ahmed, Mohammad Nasar
title Using Agent-based Modeling and Simulation to Study the Structural Behavior of DNA
title_short Using Agent-based Modeling and Simulation to Study the Structural Behavior of DNA
title_full Using Agent-based Modeling and Simulation to Study the Structural Behavior of DNA
title_fullStr Using Agent-based Modeling and Simulation to Study the Structural Behavior of DNA
title_full_unstemmed Using Agent-based Modeling and Simulation to Study the Structural Behavior of DNA
title_sort using agent-based modeling and simulation to study the structural behavior of dna
publisher University of Cincinnati / OhioLINK
publishDate 2011
url http://rave.ohiolink.edu/etdc/view?acc_num=ucin1318608371
work_keys_str_mv AT ahmedmohammadnasar usingagentbasedmodelingandsimulationtostudythestructuralbehaviorofdna
_version_ 1719433473274413056