User Interface and Modified Testbench to Support Comprehensive Analysis of Protein Structural Alignment Tools

Bibliographic Details
Main Author:	Kamepalli, Phanindra
Language:	English
Published:	University of Cincinnati / OhioLINK 2011
Subjects:	Bioinformatics Protein structural alignment tools Testbench
Online Access:	http://rave.ohiolink.edu/etdc/view?acc_num=ucin1313766325

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spelling	ndltd-OhioLink-oai-etd.ohiolink.edu-ucin13137663252021-08-03T06:15:05Z User Interface and Modified Testbench to Support Comprehensive Analysis of Protein Structural Alignment Tools Kamepalli, Phanindra Bioinformatics Protein structural alignment tools Testbench Protein structural alignment is the study of equivalences between the structures of proteins. In order to study structural alignment various tools are developed. Each tool uses different algorithms and methods to compare the structures. It is essential to find out which tool yields better results under different test cases so that more efficient tools can be developed in the future. To test the tools a comprehensive testbench data set is necessary. Our work is aimed at studying available structural alignment tools, extending previously developed testbench data set, and developing a user interface to support the modified testbench and comprehensive analysis of protein structural alignment tools.In our research we have studied all 18 protein structural alignment tools available and have done a comprehensive analysis of their performance by using our modified testbench data set. The protein pairs in the testbench data set are divided into 11 categories for comprehensive analysis of the structural alignment tools. Based on our results we ranked the tools according to their performance in each category. The overall rank is also given. Our testbench data set is configured such that, in future, if a new tool is developed and is tested on our data set, we can easily rank the tool’s performance. 2011-09-23 English text University of Cincinnati / OhioLINK http://rave.ohiolink.edu/etdc/view?acc_num=ucin1313766325 http://rave.ohiolink.edu/etdc/view?acc_num=ucin1313766325 unrestricted This thesis or dissertation is protected by copyright: some rights reserved. It is licensed for use under a Creative Commons license. Specific terms and permissions are available from this document's record in the OhioLINK ETD Center.
collection	NDLTD
language	English
sources	NDLTD
topic	Bioinformatics Protein structural alignment tools Testbench
spellingShingle	Bioinformatics Protein structural alignment tools Testbench Kamepalli, Phanindra User Interface and Modified Testbench to Support Comprehensive Analysis of Protein Structural Alignment Tools
author	Kamepalli, Phanindra
author_facet	Kamepalli, Phanindra
author_sort	Kamepalli, Phanindra
title	User Interface and Modified Testbench to Support Comprehensive Analysis of Protein Structural Alignment Tools
title_short	User Interface and Modified Testbench to Support Comprehensive Analysis of Protein Structural Alignment Tools
title_full	User Interface and Modified Testbench to Support Comprehensive Analysis of Protein Structural Alignment Tools
title_fullStr	User Interface and Modified Testbench to Support Comprehensive Analysis of Protein Structural Alignment Tools
title_full_unstemmed	User Interface and Modified Testbench to Support Comprehensive Analysis of Protein Structural Alignment Tools
title_sort	user interface and modified testbench to support comprehensive analysis of protein structural alignment tools
publisher	University of Cincinnati / OhioLINK
publishDate	2011
url	http://rave.ohiolink.edu/etdc/view?acc_num=ucin1313766325
work_keys_str_mv	AT kamepalliphanindra userinterfaceandmodifiedtestbenchtosupportcomprehensiveanalysisofproteinstructuralalignmenttools
_version_	1719433456468885504

User Interface and Modified Testbench to Support Comprehensive Analysis of Protein Structural Alignment Tools

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