Correlation of Bivariate Frailty Models and a New Marginal Weibull Distribution for Correlated Bivariate Survival Data

Bibliographic Details
Main Author: Lin, Min
Language:English
Published: University of Cincinnati / OhioLINK 2011
Subjects:
Online Access:http://rave.ohiolink.edu/etdc/view?acc_num=ucin1307321226
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spelling ndltd-OhioLink-oai-etd.ohiolink.edu-ucin13073212262021-08-03T06:14:49Z Correlation of Bivariate Frailty Models and a New Marginal Weibull Distribution for Correlated Bivariate Survival Data Lin, Min Statistics frailty model correlation bivariate marginal Weibull loglinear survival model Bayesian methods Survival analysis is widely used in many different areas. The classic models, such as Cox proportional hazards model, are frequently used to model univariate survival data. However, in biomedical studies, it is not uncommon that each study subject experience multiple events or subjects are related within some clusters. These data are called multivariate survival data. The statistical methods of these problems need to describe the dependence of observations within a subject or cluster. Frailty model is one way to approach the problem and is commonly used recently. Among the frailties, the gamma frailty is frequently used because of its analytic features. However, the gamma frailty model cannot handle the highly correlated data in some cases. In this thesis, different parametric survival models with gamma frailty and lognormal frailty have been examined in terms of correlation. Overall, lognormal frailty models perform better than gamma frailty models in many survival models. Another approach to solve multivariate survival data problem is via parametric distributions which can directly address the dependence among the data. In this thesis, a bivariate distribution with marginal Weibull distribution is proposed. Some properties of the distribution have been discussed. Weibull model with lognormal frailty, Weibull model with gamma frailty, and the marginal Weibull model are also fitted via Bayesian method and the results are compared. 2011-09-19 English text University of Cincinnati / OhioLINK http://rave.ohiolink.edu/etdc/view?acc_num=ucin1307321226 http://rave.ohiolink.edu/etdc/view?acc_num=ucin1307321226 unrestricted This thesis or dissertation is protected by copyright: all rights reserved. It may not be copied or redistributed beyond the terms of applicable copyright laws.
collection NDLTD
language English
sources NDLTD
topic Statistics
frailty model
correlation
bivariate marginal Weibull
loglinear survival model
Bayesian methods
spellingShingle Statistics
frailty model
correlation
bivariate marginal Weibull
loglinear survival model
Bayesian methods
Lin, Min
Correlation of Bivariate Frailty Models and a New Marginal Weibull Distribution for Correlated Bivariate Survival Data
author Lin, Min
author_facet Lin, Min
author_sort Lin, Min
title Correlation of Bivariate Frailty Models and a New Marginal Weibull Distribution for Correlated Bivariate Survival Data
title_short Correlation of Bivariate Frailty Models and a New Marginal Weibull Distribution for Correlated Bivariate Survival Data
title_full Correlation of Bivariate Frailty Models and a New Marginal Weibull Distribution for Correlated Bivariate Survival Data
title_fullStr Correlation of Bivariate Frailty Models and a New Marginal Weibull Distribution for Correlated Bivariate Survival Data
title_full_unstemmed Correlation of Bivariate Frailty Models and a New Marginal Weibull Distribution for Correlated Bivariate Survival Data
title_sort correlation of bivariate frailty models and a new marginal weibull distribution for correlated bivariate survival data
publisher University of Cincinnati / OhioLINK
publishDate 2011
url http://rave.ohiolink.edu/etdc/view?acc_num=ucin1307321226
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