Developing Pulsatile Flow in a Deployed Coronary Stent

Developing Pulsatile Flow in a Deployed Coronary Stent

Bibliographic Details
Main Author: Rajamohan, Divakar
Language:English
Published: University of Cincinnati / OhioLINK 2005
Subjects:
Coronary stent
restenosis
pulsatile
developing
wall shear stress
Online Access:http://rave.ohiolink.edu/etdc/view?acc_num=ucin1131920589
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spelling ndltd-OhioLink-oai-etd.ohiolink.edu-ucin11319205892021-08-03T06:10:42Z Developing Pulsatile Flow in a Deployed Coronary Stent Rajamohan, Divakar Coronary stent restenosis pulsatile developing wall shear stress A major consequence of stent implantation is restenosis that occurs due to neointimal formation. Recent evidence suggests that there are several factors such as geometry and size of vessel, and stent design that alters hemodynamic parameters, including local wall shear stress distributions, which influence the progression of restenosis. The present three-dimensional analysis of developing pulsatile flow in a deployed coronary stent quantifies hemodynamic parameters and illustrates the changes in local wall shear stress distributions and their impact on restenosis. The present model mimics the worst possible scenario where the stent is placed at the entrance region of a branched coronary artery. The present results indicate that the immediate downstream of strut intersections are areas highly susceptible to restenosis whereas a high shear stress at the strut intersection may cause platelet activation and free emboli formation. 2005 English text University of Cincinnati / OhioLINK http://rave.ohiolink.edu/etdc/view?acc_num=ucin1131920589 http://rave.ohiolink.edu/etdc/view?acc_num=ucin1131920589 unrestricted This thesis or dissertation is protected by copyright: all rights reserved. It may not be copied or redistributed beyond the terms of applicable copyright laws.
collection NDLTD
language English
sources NDLTD
topic Coronary stent
restenosis
pulsatile
developing
wall shear stress
spellingShingle Coronary stent
restenosis
pulsatile
developing
wall shear stress
Rajamohan, Divakar
Developing Pulsatile Flow in a Deployed Coronary Stent
author Rajamohan, Divakar
author_facet Rajamohan, Divakar
author_sort Rajamohan, Divakar
title Developing Pulsatile Flow in a Deployed Coronary Stent
title_short Developing Pulsatile Flow in a Deployed Coronary Stent
title_full Developing Pulsatile Flow in a Deployed Coronary Stent
title_fullStr Developing Pulsatile Flow in a Deployed Coronary Stent
title_full_unstemmed Developing Pulsatile Flow in a Deployed Coronary Stent
title_sort developing pulsatile flow in a deployed coronary stent
publisher University of Cincinnati / OhioLINK
publishDate 2005
url http://rave.ohiolink.edu/etdc/view?acc_num=ucin1131920589
work_keys_str_mv AT rajamohandivakar developingpulsatileflowinadeployedcoronarystent
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