A PROTOTYPE ON-CHIP MICRO-HEATER FOR DISPOSABLE MICRO-PCR MODULE
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| Language: | English |
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University of Cincinnati / OhioLINK
2002
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| Online Access: | http://rave.ohiolink.edu/etdc/view?acc_num=ucin1038001719 |
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ndltd-OhioLink-oai-etd.ohiolink.edu-ucin10380017192021-08-03T06:09:02Z A PROTOTYPE ON-CHIP MICRO-HEATER FOR DISPOSABLE MICRO-PCR MODULE BANERJEE, SHOMIR PCR microfabrication In this work a prototype on-chip micro-heater for thermocycling is demonstrated, which is the main component for a disposable lab-on-a-chip device than integrates a module for performing polymerase chain reaction (PCR). Several resistive micro-heaters were fabricated from gold/chrome metal films on borosilicate glass wafers and gold metal films on cyclic olefin copolymer (COC) and polycarbonate (PC) plastic wafers. Multiple resistive heaters of different geometries were designed, fabricated, and characterized to explore the feasibility of the micro-heater for a fully integrated disposable lab-on-a-chip with PCR module. Each device was characterized using custom-designed PC-based Labview virtual instruments with a data acquisition and control card. A feedback control program was implemented in Labview to characterize the dynamic response of the prototype thermocycler. The integrated on-chip micro-heater shows that the temperature transitions are short by comparison with the conventional PCR temperature routines, which would allow the fully integrated PCR module to have fast thermocycling. Optimization of the heating capacities of the on-chip micro-heater should be further investigated to make the prototype on-chip micro-heater useful, although a prototype on-chip micro-heater has been designed, fabricated, and successfully characterized to demonstrate feasibility for a fully integrated disposable PCR module. 2002 English text University of Cincinnati / OhioLINK http://rave.ohiolink.edu/etdc/view?acc_num=ucin1038001719 http://rave.ohiolink.edu/etdc/view?acc_num=ucin1038001719 unrestricted This thesis or dissertation is protected by copyright: all rights reserved. It may not be copied or redistributed beyond the terms of applicable copyright laws. |
| collection |
NDLTD |
| language |
English |
| sources |
NDLTD |
| topic |
PCR microfabrication |
| spellingShingle |
PCR microfabrication BANERJEE, SHOMIR A PROTOTYPE ON-CHIP MICRO-HEATER FOR DISPOSABLE MICRO-PCR MODULE |
| author |
BANERJEE, SHOMIR |
| author_facet |
BANERJEE, SHOMIR |
| author_sort |
BANERJEE, SHOMIR |
| title |
A PROTOTYPE ON-CHIP MICRO-HEATER FOR DISPOSABLE MICRO-PCR MODULE |
| title_short |
A PROTOTYPE ON-CHIP MICRO-HEATER FOR DISPOSABLE MICRO-PCR MODULE |
| title_full |
A PROTOTYPE ON-CHIP MICRO-HEATER FOR DISPOSABLE MICRO-PCR MODULE |
| title_fullStr |
A PROTOTYPE ON-CHIP MICRO-HEATER FOR DISPOSABLE MICRO-PCR MODULE |
| title_full_unstemmed |
A PROTOTYPE ON-CHIP MICRO-HEATER FOR DISPOSABLE MICRO-PCR MODULE |
| title_sort |
prototype on-chip micro-heater for disposable micro-pcr module |
| publisher |
University of Cincinnati / OhioLINK |
| publishDate |
2002 |
| url |
http://rave.ohiolink.edu/etdc/view?acc_num=ucin1038001719 |
| work_keys_str_mv |
AT banerjeeshomir aprototypeonchipmicroheaterfordisposablemicropcrmodule AT banerjeeshomir prototypeonchipmicroheaterfordisposablemicropcrmodule |
| _version_ |
1719431710896029696 |