Production of Advanced Materials from Renewable Feedstocks: Chemical Modification of Cellulose through TEMPO Catalyzed Oxidation

Production of Advanced Materials from Renewable Feedstocks: Chemical Modification of Cellulose through TEMPO Catalyzed Oxidation

Bibliographic Details
Main Author: Hamdan, Hamed Mohamed
Language:English
Published: University of Toledo / OhioLINK 2018
Subjects:
Chemical Engineering
Online Access:http://rave.ohiolink.edu/etdc/view?acc_num=toledo1533130410448935
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spelling ndltd-OhioLink-oai-etd.ohiolink.edu-toledo15331304104489352021-08-03T07:07:54Z Production of Advanced Materials from Renewable Feedstocks: Chemical Modification of Cellulose through TEMPO Catalyzed Oxidation Hamdan, Hamed Mohamed Chemical Engineering The goal of this project is to Investigate the effect of cellulose degree of polymerization (DP) and structure on production of polyglucuronic acid by 4-acetamido-2,2,6,6-tetramethylpiperidine1-oxyl (TEMPO) oxidation. Polyglucuronic acid has anti-microbial activities. It can be used as a hemostatic agent post-surgery to control bleeding from wounds, and in oncoplastic breast surgery to prevent cosmetic defects. Moreover, polyglucuronic acid can be used in drug delivery. Glucuronic acid (hydrolysis product) can be used as an intermediate to produce vitamin C and provide a building block for hyaluronic acid. Further oxidation of glucuronic acid can produce glucaric acid. Glucaric acid can be used in bio-derived polymers and serves as a top Department of Energy (DOE) platform chemical.The production of polyglucuronic acid was assessed using Avicel (DP 150-225) and cotton linters (DP 1000-6500). Avicel was treated with ionic liquid and with incubation with NaOH (mercerization). Cotton linters were treated with ionic liquid. Avicel was oxidized for 72 hours using TEMPO catalyst to produce polyglucuronic acid at 60°C, pH4.8 with the yield of 71%, 47% and 19% for IL-treated, mercerized and untreated Avicel (crystalline Avicel), respectively. Similarly, cotton linters were oxidized for 72 hours using TEMPO catalyst to produce polyglucuronic acid at 60°C, pH 4.8, with the yield of 57%. Moreover, rapid oxidation of IL-treated Avicel occurred at 80°C after 12 hours with yield of 67%. The amorphous structure of IL-treated Avicel let to improved cellulose oxidation results. The higher DP of IL-treated cotton linters appears to impede transition to an amorphous substrate and subsequent oxidation. 2018 English text University of Toledo / OhioLINK http://rave.ohiolink.edu/etdc/view?acc_num=toledo1533130410448935 http://rave.ohiolink.edu/etdc/view?acc_num=toledo1533130410448935 unrestricted This thesis or dissertation is protected by copyright: all rights reserved. It may not be copied or redistributed beyond the terms of applicable copyright laws.
collection NDLTD
language English
sources NDLTD
topic Chemical Engineering
spellingShingle Chemical Engineering
Hamdan, Hamed Mohamed
Production of Advanced Materials from Renewable Feedstocks: Chemical Modification of Cellulose through TEMPO Catalyzed Oxidation
author Hamdan, Hamed Mohamed
author_facet Hamdan, Hamed Mohamed
author_sort Hamdan, Hamed Mohamed
title Production of Advanced Materials from Renewable Feedstocks: Chemical Modification of Cellulose through TEMPO Catalyzed Oxidation
title_short Production of Advanced Materials from Renewable Feedstocks: Chemical Modification of Cellulose through TEMPO Catalyzed Oxidation
title_full Production of Advanced Materials from Renewable Feedstocks: Chemical Modification of Cellulose through TEMPO Catalyzed Oxidation
title_fullStr Production of Advanced Materials from Renewable Feedstocks: Chemical Modification of Cellulose through TEMPO Catalyzed Oxidation
title_full_unstemmed Production of Advanced Materials from Renewable Feedstocks: Chemical Modification of Cellulose through TEMPO Catalyzed Oxidation
title_sort production of advanced materials from renewable feedstocks: chemical modification of cellulose through tempo catalyzed oxidation
publisher University of Toledo / OhioLINK
publishDate 2018
url http://rave.ohiolink.edu/etdc/view?acc_num=toledo1533130410448935
work_keys_str_mv AT hamdanhamedmohamed productionofadvancedmaterialsfromrenewablefeedstockschemicalmodificationofcellulosethroughtempocatalyzedoxidation
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